Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis. Images in Clinical Medicine from The New England Journal of Medicine — Heerfordt’s Syndrome, or Uveoparotid Fever. Heerfordt’s syndrome is a rare manifestation of sarcoidosis characterized by the presence of facial nerve palsy, parotid gland enlargement.

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Sarcoidosis is a systemic disease characterized by hferfordt formation. Facial palsy in Heerfordt’s syndrome: As uveitis and BHL had been previously diagnosed, she underwent a detailed examination for sarcoidosis in the Department of Respiratory Medicine in our hospital.

New England Journal of Medicine. Treatment depends on the severity of systemic impairment. The prognosis of sarcoidosis varies according to disease duration, severity and the organs affected. A year-old female patient reported having right peripheral facial paralysis, with no apparent cause. The likelihood of permanent paralysis increases in patients who syncrome not treated with corticosteroids.

Salivary gland involvement likely led to the pharyngitis seen on esophagogastroduodenoscopy and the patient’s difficulty swallowing. This is an open heertordt article distributed under the Creative Commons Attribution Licensewhich permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Heerfordt syndrome | QJM: An International Journal of Medicine | Oxford Academic

Journal of the American Academy of Physician Assistants. Prominent hilar markings were identified on chest x-ray, but no focal opacity was seen. Blood cultures, tuberculosis testing, and HIV antibody testing were negative. Loading Stack – 0 images remaining. View at Google Scholar J.

Log in Sign up. As with other manifestations of sarcoidosis, corticosteroids are the mainstay of treatment. In tuberculosis, the mastoid, middle ear, or petrous bone is often involved 12. Please review our privacy policy. Two months after discharge, her facial nerve palsy, parotitis, fevers, and uveitis had resolved. Edit article Share article View revision history.

The diagnosis of HWS is clinical. From Wikipedia, the free encyclopedia.

Papule on the forehead, with a translucent appearance and red-brownish color. Her posterior pharynx was erythematous, but no areas of oropharyngeal fluctuance were noted. In the United States, sarcoidosis has a prevalence of approximately 10 cases perwhites and 36 cases perblacks. Synonyms or Alternate Spellings: By using this site, you agree to the Terms of Use and Privacy Policy. No nodules were detected and diffuse swelling of parotid gland was observed in the US examination.


As the prognosis for facial nerve palsy in sarcoidosis is thought to be good [ 1415 ], detailed examination, including bronchoscopic biopsy, should proceed in advance of the treatment for facial nerve palsy. It is normally self-limiting, with cure achieved between 12 and 36 syndromd, but some prolonged cases have been reported. Angiotensin I-converting enzyme ACE for sarcoidosis diagnosis.

The Heerfordt-Waldenström syndrome as an initial presentation of sarcoidosis

Some observations of uveoparotitis and allied conditions with special reference to the symptoms from the nervous system. A year-old woman presented with left facial nerve palsy, bilateral hearing loss, and swelling of her bilateral parotid glands.

The authors declare that there is no conflict of interests regarding the publication of this paper. Corticosteroid treatment in pulmonary sarcoidosis: